Mass spectrometry

Mass spectrometry is a powerful analytical technique that is used to determine the molecular weight and calculate the molecular formula using high-resolution mass spectrometry. The MS principle consists of ionizing chemical compounds to generate charged molecules or molecule fragments and measuring their mass-to-charge ratios. The combination of liquid chromatography (LC), photodiode-array UV-Vis detector, and atmospheric pressure ionization mass spectrometry (APIMS) has proven to be a useful on-line system for establishing the identity of components in given test samples. In the recent era, tandem mass spectrometry (MS/MS) is used to identify unknown compounds, to quantify known compounds, and to elucidate the structure and chemical properties of molecules.

• Electrospray Ionization(ESI)-Mass Spectrometry
• Desorption Electrospray Ionization (DESI) Mass Spectrometry
• Atmospheric Pressure Chemical Ionization(APCI)-Mass Spectrometry
• High-Performance Liquid Chromatography-Mass Spectrometry(LC-MS)
• High-Performance Liquid Chromatography-Tandem Mass Spectrometry(LC-MS/MS)
• Electrospray Ionization-High Resolution Mass Spectrometry (ESI-HRMS)
• Ultra-high Performance Liquid Chromatography- High Resolution Mass Spectrometry(LC-HRMS)
• Ultra-high Performance Liquid Chromatography- High Resolution Tandem Mass Spectrometry(LC-HRMS/MS)
• Ion mobility spectrometry(IMS)
• DESI Mass Spectrometry-Imaging
• A library of the MS/MS spectrum(https://tmsdatabase.cdri.res.in)

• Non-volatile, polar molecules (ESI) or moderate polar molecules (APCI)
• Mass range 100-2000 Da
• Provide [M+H]+ ion or adduct ions
• MS/MS fragments

• Non-volatile, polar molecules (ESI) or moderate polar molecules (APCI)
• Mass range 100-3000 Da
• Provide [M+H]+ ion with accurate mass measurement or adduct ions
• MS/MS fragments with accurate mass measurement
• Ion mobility spectrometry (IMS)
• DESI Mass Spectrometry-Imaging